How to create and use multiple profiles in Google Chrome
The first step is to add a command line switch to your Google Chrome (or Chromium) shortcut: --enable-udd-profiles. If you need help figuring out how to add a switch, check our tutorial post -- Windows and Linux users follow pretty much the same steps, while Mac users may just want to launch the command from a terminal session.
Once you've added the switch, double-click your shortcut to launch Chrome. Once it's loaded, press control + M to invoke the profile selection menu. You'll have two options initially: default (what you're using right now) and new profile.
You'll also have the option of creating a desktop shortcut to open Chrome with your new profile. You may notice a little weirdness on your taskbar if you're using Windows 7 and running multiple windows with different profiles simultaneously. One of my icons showed a jumplist, the other did not -- but it did show per-tab thumbnail previews (and the original did not).
While creating new profiles and switching between them isn't that hard using Chrome itself, managing them isn't so easy. For that task, ChromeDeck is actually quite handy -- just make sure you've got .Net 4.0 installed.