Back4Sure makes it easy to backup files to removable disks
One of the more irritating problems in trying to automate backup to a USB drive is that the drive letter may randomly change. There are utilities to keep this from happening, but they can be a bit of a hassle to set up.
Back4Sure is a simple backup utility with all of the generic features you would expect, and one nice extra: It lets you specify the destination volume by label (i.e, "SteveUSB" or whatever nifty name you gave your drive), rather than by letter. Backup jobs can be started from the command line, which means you can create an Autorun file for your USB device of choice and have backup run automagically whenever you plug it in.
Back4Sure is portable, freeware, and available in both English and German.