Wine 1.0 pops the cork: Run Windows apps on Linux
Wine 1.0 installation instructions are available for a whole slew of distributions, including Fedora, Red Hat, SUSE, Mandriva, Slackware, Ubuntu, Debian, FreeBSD and Solaris. Or if you wait a few days there's a good chance the latest version of Wine will be added to your distro's official repositories.
To be perfectly honest, you might not notice a ton of changes from previous versions of Wine. But the latest build does include a ton of fixes for specific applications including WinRAR, Skype, Dragon Naturally Speaking, and video games like Call of Duty 1.0